Azelaic Acid for Rosacea: What the Science Says
Reviewing clinical studies on azelaic acid and its benefits for rosacea-prone skin.
Dr. James Liu, PhD
May 10, 2024 · 8 min read
Azelaic acid is one of the most studied topical options for rosacea. It has anti-inflammatory and antimicrobial properties and is often recommended for papules, pustules, and background redness.
In clinical trials, prescription-strength azelaic acid (typically 15% gel or foam) has been shown to reduce inflammatory lesions and improve overall rosacea severity scores over 12 weeks.
Over-the-counter formulas (often 10%) can still help some people, but results vary. Start slowly — a few nights a week — and always pair with a gentle moisturizer and daily SPF.
Talk with your dermatologist before combining azelaic acid with other actives, especially during a flare.
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